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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP7
All Species:
39.09
Human Site:
T489
Identified Species:
61.43
UniProt:
Q93009
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93009
NP_003461.2
1102
128302
T489
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Chimpanzee
Pan troglodytes
XP_510806
1102
128297
T489
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536979
1086
126326
T473
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6A4J8
1103
128457
T490
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Rat
Rattus norvegicus
Q4VSI4
1103
128413
T490
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506396
1145
132881
T532
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Chicken
Gallus gallus
Q6U7I1
1101
128279
T489
D
D
V
V
S
R
C
T
K
E
E
A
I
E
H
Frog
Xenopus laevis
NP_001121282
534
61718
Zebra Danio
Brachydanio rerio
XP_691215
1103
128646
T490
D
D
V
V
S
R
C
T
K
E
E
A
T
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VYQ8
1129
130428
K516
D
V
V
S
S
C
R
K
Q
E
A
I
E
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q7JKC3
1135
131579
T476
D
D
V
V
S
R
T
T
T
D
D
A
I
V
S
Sea Urchin
Strong. purpuratus
XP_780569
1189
136707
T584
D
D
V
V
S
R
C
T
K
M
E
A
I
D
N
Poplar Tree
Populus trichocarpa
XP_002316470
1116
130731
G489
A
L
E
E
Q
Y
G
G
E
E
E
L
P
Q
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84WU2
1115
130630
G490
A
L
E
E
Q
Y
G
G
E
E
E
L
P
Q
N
Baker's Yeast
Sacchar. cerevisiae
P50101
1230
143545
L504
E
N
F
G
C
D
R
L
P
D
E
K
V
R
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.7
N.A.
99
99
N.A.
92.4
95.9
46
94
N.A.
48.5
N.A.
34.4
54.5
Protein Similarity:
100
99.9
N.A.
98
N.A.
99.7
99.8
N.A.
94.7
97.9
47.4
96.8
N.A.
67.5
N.A.
52.5
69.2
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
93.3
N.A.
26.6
N.A.
60
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
0
93.3
N.A.
46.6
N.A.
73.3
93.3
Percent
Protein Identity:
36.9
N.A.
N.A.
36.5
29.4
N.A.
Protein Similarity:
54.3
N.A.
N.A.
54.7
47.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
0
0
0
0
0
0
0
0
0
7
67
0
0
0
% A
% Cys:
0
0
0
0
7
7
60
0
0
0
0
0
0
0
0
% C
% Asp:
74
67
0
0
0
7
0
0
0
14
7
0
0
7
0
% D
% Glu:
7
0
14
14
0
0
0
0
14
74
80
0
7
54
0
% E
% Phe:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
14
14
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
60
0
0
% I
% Lys:
0
0
0
0
0
0
0
7
60
0
0
7
0
0
0
% K
% Leu:
0
14
0
0
0
0
0
7
0
0
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
14
0
0
% P
% Gln:
0
0
0
0
14
0
0
0
7
0
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
67
14
0
0
0
0
0
0
7
0
% R
% Ser:
0
0
0
7
74
0
0
0
0
0
0
0
0
0
7
% S
% Thr:
0
0
0
0
0
0
7
67
7
0
0
0
7
0
14
% T
% Val:
0
7
74
67
0
0
0
0
0
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _